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TirzepatideReport

Tirzepatide monograph · Evidence review

Joi + Blokes Tirzepatide Review: Cost, a Strong Trustpilot Record & Honest Verdict (2026)

An honest 2026 review of Joi + Blokes tirzepatide — separate gendered programs, a genuinely strong Trustpilot record, and a quarterly commitment.

Researched & written by Alan Pierce · last updated

Clinical Pharmacology Writer

FDA warning letter
FDA issued Joi and Blokes dba Joi + Blokes a warning letter in June 2026 (False & Misleading Claims/Misbranded (Telehealth)). Read the letter on FDA’s own warning-letter database.

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Editorial pick

CoreAge Rx

$149/mo flat

Doctor-reviewed tirzepatide with one flat price and built-in human support.

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vs median
$120/mo below the $269 median
Market
$109–$429/mo across 396 providers
Dispensed
Compounded tirzepatide (503A)

Popular alternative

Shed (ShedRx)

Compounded tirzepatide from $239 with the widest set of formats here — injections, liquid drops, lozenges, and a real brand Zepbound pathway.

$299/mo

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Joi + Blokes: $299/month for tirzepatide on the quarterly plan, and genuine intro pricing at $149/month for the first month — both confirmed present on the site, alongside a real hormone-plus-GLP-1 integrated model. Every fact here comes from the company's own published program.

What Joi + Blokes is

Joi + Blokes is a hormone-first telehealth platform, with separate parallel programs for women (Joi) and men (Blokes) — genuinely rarer than the gender-agnostic default in this category — now expanded to compounded GLP-1s. A live video visit is required before a prescription, and labs are required.

§ Joi + Blokes — Confirmed Pricing and Trustpilot Record

ItemDetail
Tirzepatide, first month$149/mo
Tirzepatide, ongoing$299/mo quarterly
Trustpilot4.6/5, 1,254+ reviews
Verified: $149/mo first month, $299/mo quarterly plan ongoing. 4.6/5 Trustpilot, 1,254+ reviews.

What Joi + Blokes costs

$299/month for tirzepatide on the quarterly plan, with a $149/month first-month discount confirmed present, and semaglutide at $199/month ongoing / $99/month first month. months 2+ cost more than the intro price, and pricing differs in NY and NJ — confirm your state's specific rate.

A genuinely strong Trustpilot record

This is a real positive: 4.6/5 from 1,254+ Trustpilot reviews — among the strongest independent review signals this site has documented, backing up the program's real-world reputation.

The brand-vs-compounded question

Joi + Blokes dispenses compounded tirzepatide on the GLP-1 side — no FDA-approved Wegovy, though Zepbound is available for a separate visit fee. Compounded tirzepatide is pharmacy-made, not itself an FDA-approved finished drug, and was not the specific product studied in the pivotal trials. See our guide to whether compounded tirzepatide is still legal in 2026 for the regulatory picture.

How the care model holds up

Joi + Blokes's real strengths: genuinely separate women's and men's programs, a strong independent Trustpilot record, and a monthly price that bundles medication, dosing support, clinician consults, and health coaching, plus integrated hormone and GLP-1 protocols for patients on testosterone or perimenopausal care. The trade-offs: it's billed quarterly rather than month-to-month, pricing differs by state (NY and NJ specifically), coverage is zip-code gated rather than publicly listed, and months 2+ cost more than the intro rate. As with any GLP-1 program, confirm your specific state's price and read the quarterly commitment terms before committing; tirzepatide carries labeled warnings for acute pancreatitis, gallbladder disease, and a boxed thyroid C-cell tumor warning — see our guides on Zepbound side effects, the gallbladder risk, and the thyroid cancer warning.

Does the drug work? (Separate from the provider)

Judge the provider on price, oversight and disclosure; judge the molecule on its trials. Tirzepatide's are strong — roughly 15–21% of body weight over 72 weeks in SURMOUNT-11, and better than semaglutide head-to-head2 — but they were run on the brand drug at FDA-approved doses. Our tirzepatide evidence guide has the full picture.

The honest verdict

Joi + Blokes's separate gendered programs and genuinely strong Trustpilot record are real positives this review confirmed directly, and the bundled coaching model is a genuine differentiator for patients on hormone protocols. Confirm your state's specific pricing before committing to the quarterly plan. For a similarly bundled program without gender-specific framing, compare it against Elara Health and Wellness or DrBrainRx. For a provider with a genuinely verified LegitScript seal and a fully published price list, but a real billing-cycle and refund-clawback catch, see Luvo Health. See our best tirzepatide providers ranking for the full field.

Frequently asked questions

How much does tirzepatide cost through Joi + Blokes?

$149/month for the first month, rising to $299/month on the ongoing quarterly plan.

Does Joi + Blokes have separate programs for men and women?

Yes — Joi for women and Blokes for men, a genuine differentiator most GLP-1 telehealth doesn't offer.

How is Joi + Blokes rated on independent review sites?

4.6/5 from 1,254+ Trustpilot reviews — among the strongest independent review signals this site has documented.

References(2)

  1. Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, and the SURMOUNT-1 Investigators (2022). Tirzepatide Once Weekly for the Treatment of Obesity.. New England Journal of Medicine. PMID: 35658024. https://pubmed.ncbi.nlm.nih.gov/35658024/
  2. Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Bays HE, et al. (2025). Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5).. New England Journal of Medicine. PMID: 40353578. https://pubmed.ncbi.nlm.nih.gov/40353578/

About the author

Alan Pierce

Clinical Pharmacology Writer

About Tirzepatide Report · How we verify prices · This page last updated August 2026

Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.