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Zepbound Cost Calculator

Monthly out-of-pocket estimator

What you actually pay for Zepbound (tirzepatide) swings by hundreds of dollars depending on three things: the format you buy (cheaper self-pay vial vs. convenient pen), your insurance route, and whether a telehealth service stacks a membership fee on top. This tool combines the current-2026 LillyDirect and savings-card prices from our cost guides into a single monthly and annual estimate. It is a cost estimate, not a dosing tool — the dose tier only looks up a price.

Read before you use this

This is an estimate only — not financial or medical advice, and not a price quote. Drug prices change frequently, and the figures here mirror current-2026 LillyDirect and Lilly savings-card numbers that can move at any time. The manufacturer savings card has eligibility rules — it requires commercial insurance and excludes anyone on Medicare, Medicaid, the VA or TRICARE — and your real copay on a covered plan depends on your specific benefits. Always verify the current price directly on LillyDirect and with your insurer or pharmacy before deciding. Zepbound is prescription-only; this tool does not recommend a dose, a product, or a course of treatment.

Format
Vials are the cheaper self-pay route (LillyDirect, you draw the dose); pens carry the flat ~$1,086 cash list price.
Dose tier
Used only to look up the self-pay vial price tier — not a dose recommendation. 2.5 mg is the starting dose; 5 mg is its own tier; 7.5–15 mg share a tier (12.5 and 15 mg carry the ~45-day refill rule).
Insurance / discount route
The savings card requires commercial insurance and excludes Medicare, Medicaid, the VA and TRICARE — those plans use the cash self-pay route.
Some telehealth services add a separate platform or membership fee on top of the medication. Enter it here if yours does; leave it at $0 if you buy direct from LillyDirect.

Estimated monthly out-of-pocket

$299/ month

About $3,588 a year. This is an estimate — verify the current price on LillyDirect.

Medication / month
$299
LillyDirect self-pay vial
Membership / month
$0
None entered
Annual / year
$3,588
monthly × 12

Cash self-pay vial via LillyDirect — the cheapest legitimate brand route for uninsured or government-insured patients (you draw the dose with a syringe).

How it is estimated. Cash self-pay vials use the LillyDirect 2026 tier prices (2.5 mg ≈ $299, 5 mg ≈ $399, 7.5–15 mg ≈ $449 per 28-day supply); the 12.5 mg and 15 mg vials show a range up to ~$849–$1,049 to reflect the ~45-day refill rule. The cash pen uses the flat ~$1,086 list price. A commercial plan that covers Zepbound plus the savings card is shown as low as $25; a commercial plan that does not cover it (savings-card route) is ~$299. Any membership fee is added, then multiplied by 12 for the annual figure. Worked example: cash · 2.5 mg vial · $0 membership = $299/mo = $3,588/yr.

Understand the price before you commit

A monthly number is the easy part. Which route is cheapest for you, whether your insurance covers it, and where to buy brand Zepbound safely are the parts that actually decide your cost — read these next:

This calculator is informational and not financial or medical advice. It performs simple arithmetic against published, current-2026 list and savings prices and does not account for your specific plan benefits, deductible, pharmacy, region, or eligibility for the savings card. Prices and program terms change frequently — confirm the current figures on LillyDirect and with your insurer before purchasing. Zepbound is available by prescription after clinician review; talk to a licensed provider about whether it is appropriate for you.