Tirzepatide monograph · Evidence review
Immortals Tirzepatide Review: Cost, Founded by Bryan Johnson & Honest Verdict (2026)
An honest 2026 review of Immortals tirzepatide — a genuine LegitScript seal, microdosing-only, and a founder connection to Bryan Johnson.
Researched & written by Alan Pierce · last updated
Clinical Pharmacology Writer
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CoreAge Rx
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- $120/mo below the $269 median
- Market
- $109–$429/mo across 396 providers
- Dispensed
- Compounded tirzepatide (503A)
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RxSpan MD
Physician-founded, LegitScript-certified, and one of the few programs that names every 503A pharmacy it uses.
$329/mo injection (month-to-month)
Check RxSpan MD availabilityImmortals: $180/month for its tirzepatide microdose tier, a genuine LegitScript certification with a specific verifiable ID (50458743), and a real, confirmed founder connection to longevity figure Bryan Johnson. Every fact here comes from the company's own published program.
What Immortals is
Immortals is a LegitScript-certified longevity telehealth platform, with a verifiable LegitScript ID (50458743). It was founded by Bryan Johnson, the longevity figure behind the "Don't Die" / Blueprint protocol, alongside Kate Tolo, with clinical leadership by Dr. Carl Seger, M.D., a preventive/longevity medicine physician — all confirmed present on the site.
§ Immortals — Confirmed Founders and Microdose Pricing
| Item | Detail |
|---|---|
| LegitScript ID | 50458743 |
| Founders | Bryan Johnson, Kate Tolo |
| Tirzepatide microdose | $180/mo, quarterly billing |
What Immortals costs
$180/month for the tirzepatide microdose tier, with a $167/month figure also present for semaglutide microdosing — both. Pricing is billed quarterly, consistent with roster data citing a $501-$540 per quarter upfront commitment with no monthly flexibility.
Microdosing only — a real efficacy distinction
This is the most important thing to understand about Immortals: it dispenses microdose (sub-clinical dose) tirzepatide and semaglutide, co-formulated with Glycine and B12 — not the standard therapeutic doses studied in the SURMOUNT and STEP trials cited below. Microdosing GLP-1s is a genuinely different protocol with lower expected weight-loss efficacy than standard-dose regimens; don't assume the trial results below apply proportionally at this dose.
The brand-vs-compounded question
Immortals dispenses compounded tirzepatide only — at microdose levels specifically. Compounded tirzepatide is pharmacy-made, not itself an FDA-approved finished drug, and was not the specific product studied in the pivotal trials. See our guide to whether compounded tirzepatide is still legal in 2026 for the regulatory picture.
How the care model holds up
Immortals's real strengths: a genuine, verifiable LegitScript certification, named founders and clinical lead (Bryan Johnson, Kate Tolo, Dr. Carl Seger), a physician consult and prescription bundled into the price with no added fees, and unlimited provider messaging for 12 months. The trade-offs: the microdose framing means sub-clinical doses with lower expected weight-loss efficacy than standard protocols, it's quarterly-commitment only with no monthly flexibility, state availability isn't specifically listed, labs aren't included, and the compounding pharmacy isn't named. As with any GLP-1 program, and especially a microdosing one, understand that the efficacy data cited below was established at standard clinical doses, not the sub-clinical amounts Immortals dispenses; tirzepatide carries labeled warnings for acute pancreatitis, gallbladder disease, and a boxed thyroid C-cell tumor warning — see our guides on Zepbound side effects, the gallbladder risk, and the thyroid cancer warning.
Does the drug work? (Separate from the provider)
Judge the provider on price, oversight and disclosure; judge the molecule on its trials. Tirzepatide's are strong — roughly 15–21% of body weight over 72 weeks in SURMOUNT-11, and better than semaglutide head-to-head2 — but they were run on the brand drug at FDA-approved doses. Our tirzepatide evidence guide has the full picture.
The honest verdict
Immortals's genuine LegitScript certification and named, credible leadership (Bryan Johnson, Dr. Carl Seger) are real trust signals this review confirmed directly, but its microdosing-only model means you're not getting the standard-dose protocol the cited trials actually studied — understand that distinction before committing to the quarterly plan. For a provider offering standard therapeutic doses this review has independently compare CoreAge Rx or bmiMD. Another provider with a low-dose longevity tier is Levers Health, though this review couldn't verify it live. See our best tirzepatide providers ranking for the full field.
Frequently asked questions
Who founded Immortals?
Bryan Johnson and Kate Tolo, both on the site, with clinical leadership by Dr. Carl Seger, M.D.
How much does tirzepatide cost through Immortals?
$180/month for the microdose tier, billed quarterly ($501-$540 per quarter upfront) with no monthly flexibility.
Does Immortals offer standard therapeutic doses?
No — it dispenses microdose (sub-clinical) tirzepatide and semaglutide only, not the standard doses studied in the SURMOUNT and STEP trials.
References(2)
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, and the SURMOUNT-1 Investigators (2022). Tirzepatide Once Weekly for the Treatment of Obesity.. New England Journal of Medicine. PMID: 35658024. https://pubmed.ncbi.nlm.nih.gov/35658024/
- Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Bays HE, et al. (2025). Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5).. New England Journal of Medicine. PMID: 40353578. https://pubmed.ncbi.nlm.nih.gov/40353578/
About the author
Alan Pierce
Clinical Pharmacology Writer
About Tirzepatide Report · How we verify prices · This page last updated August 2026
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.
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