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Tirzepatide monograph · Evidence review

Clume Health Tirzepatide Review: $259/Month, Oral or Injectable (2026)

Clume Health charges $259 a month for full-dose tirzepatide, oral or injectable, and prices semaglutide identically. The homepage $199 matches nothing.

Researched & written by Alan Pierce · last updated

Clinical Pharmacology Writer

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$130/mo below the $279 median
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$109–$429/mo across 388 providers
Dispensed
Compounded tirzepatide (503A)

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Clume Health charges $259 a month, month to month, for full-dose tirzepatide, and the identical $259 buys full-dose semaglutide in either an oral or an injectable form, so the molecule is a clinical decision rather than a budget one. The figure sits on the program page before the intake asks anything, read live on 1 September 2026.1

What $259 covers, and what the cheaper numbers cost you

The inclusion list puts the treatment plan, the consultation and ongoing oversight, the medication and delivery inside that one figure, and no membership or shipping fee appears anywhere. Two smaller numbers share the same cards, and both are commitments rather than rates. A rate of $186 a month requires a 52-week plan, a year bought up front, while $200 a month belongs to the microdose and maintenance track whose standing rate is $219. A reader scanning either card sees two monthly figures side by side, separated only by that qualifier.

§ Clume Health — the published program prices, read 1 September 2026

ProgramMonth to monthThe cheaper rate, and what it requires
Signature — full dose, oral or injectable$259 a month$186 a month, only on a 52-week plan
Microdose and Maintain$219 a month$200 a month, only on a 12-week plan
NAD+ and sermorelinnot published$216 a month, only on a 12-week plan
The month-to-month column is what a first month costs. Everything in the third column is a commitment length, not a billing cycle, and both columns print on the same card.

The two homepage figures that match nothing Clume sells

The homepage advertises GLP-1 and microdose programs starting at $199 a month and cellular optimization at $159, but the page that actually prices them shows floors of $259, $219 and $216. Each hero figure carries an asterisk that resolves to nothing: a census on 1 September found no footnote text on the page.

Four pharmacies named, and a designation nobody states

The Terms of Use list four dispensing pharmacies outright, each with a street address and a phone number: RedRock Pharmacy, Health Warehouse, Precision Medicine and Triad Rx. That is a real disclosure, and it stops short twice. The Terms never say which pharmacy fills which program, and they reserve the right to move a prescription among the four for availability, pricing or operational reasons. A census of the homepage, the program page and the three legal pages found no instance of 503A, 503B or NPI, and no clinician is named.

The brand-vs-compounded question

Clume sells no brand product, and it never says outright that its tirzepatide is compounded. The word compounding occurs once, inside the Terms' definition of a pharmacy. A compounded drug is made by a pharmacy, holds no FDA approval as a finished product, and is not what the pivotal trials measured — our guide to whether compounded tirzepatide is still legal in 2026 sets out where that stands.

How the care model holds up

The strengths are a price readable before you commit and a refund if a clinician disqualifies you. The paperwork is thinner. The refund policy describes a bundled price including a 24/7 patient support line, while no Clume phone number exists anywhere and support runs by email. Cancellation needs 72 hours' notice before the next billing date, the month you cancel in is not refunded, and a prepaid plan is refunded only for months in which nothing shipped.

Does the drug work? (Separate from the provider)

Judge the seller on what it publishes and how it bills; judge the molecule on its trials. Tirzepatide's are strong — roughly 15% to 21% of body weight over 72 weeks in SURMOUNT-12, and ahead of semaglutide head to head in SURMOUNT-53 — though both trials used the brand product. Our tirzepatide evidence guide has the full picture.

The honest verdict

Clume is easy to price and hard to place. One figure covering two molecules and two routes helps anyone weighing the clinical question apart from the money. A homepage advertising $199 for programs that start at $259 should be fixed rather than footnoted. Lean Meds charges $109 a month and names its four pharmacies as 503A facilities, which is the one line Clume leaves blank, and Collective splits its bill rather than bundling it, at $69 a month for the medication and $199 a year for the membership that unlocks it. The ranked best tirzepatide providers list sets all three against the field.

Frequently asked questions

How much does tirzepatide cost at Clume Health?

$259 a month, month to month, for full-dose tirzepatide, oral or injectable; semaglutide costs the same.

Why does the homepage say $199?

It matches nothing Clume sells; the real floors are $259 and $219, and the asterisk has no footnote.

Does Clume name its pharmacy?

Yes, four of them, with addresses and phone numbers. No 503A or 503B designation appears anywhere.

References(3)

  1. North Atelier LLC, doing business as Clume Health (2026). Program pricing, Terms of Use, Privacy Policy and Refund and Cancellations Policy. clumehealth.com. https://www.clumehealth.com/
  2. Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, and the SURMOUNT-1 Investigators (2022). Tirzepatide Once Weekly for the Treatment of Obesity.. New England Journal of Medicine. PMID: 35658024. https://pubmed.ncbi.nlm.nih.gov/35658024/
  3. Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Bays HE, et al. (2025). Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5).. New England Journal of Medicine. PMID: 40353578. https://pubmed.ncbi.nlm.nih.gov/40353578/

About the author

Alan Pierce

Clinical Pharmacology Writer

About Tirzepatide Report · How we verify prices · This page last updated September 2026

Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.

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