Tirzepatide monograph · Evidence review
ZYP Medical Tirzepatide Review: Cost, a Low Consult Fee & Honest Verdict (2026)
An honest 2026 review of ZYP Medical tirzepatide — flat pricing with a low $50 consult and both injectable and oral options, across just six states.
Researched & written by Alan Pierce · last updated
Clinical Pharmacology Writer
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Check availability- vs median
- $120/mo below the $269 median
- Market
- $109–$429/mo across 396 providers
- Dispensed
- Compounded tirzepatide (503A)
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He & She MD
He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral), with brand-name…
$299/mo (month to month, compounded; every lower rate is a prepaid term)
Check He & She MD availabilityZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states, with care from a board-certified family nurse practitioner. Every fact here comes from the company's own published program.
What ZYP Medical is
ZYP Medical offers both injectable and oral tirzepatide options, with a live video visit required before a prescription. It's transparent flat-rate pricing that includes medication and shipping, with no membership fees and pricing that decreases as treatment progresses.
§ ZYP Medical — Low Consult, Six-State Reach
| Item | Detail |
|---|---|
| Tirzepatide | $233/mo |
| Initial consult | $50 |
| States served | 6 (NE, IA, SD, KS, CO, AZ) |
What ZYP Medical costs
$233/month, with a notably low $50 initial one-hour consultation — cheaper than many competitors' intake fees.
The brand-vs-compounded question
ZYP Medical dispenses compounded tirzepatide only. Compounded tirzepatide is pharmacy-made, not itself an FDA-approved finished drug, and was not the specific product studied in the pivotal trials. See our guide to whether compounded tirzepatide is still legal in 2026 for the regulatory picture.
How the care model holds up
ZYP Medical's real strengths is a low $50 initial consultation, transparent flat-rate pricing including medication and shipping, no membership fees, pricing that decreases as treatment progresses, and both injectable and oral formats. The trade-offs: it's available in only six states (NE, IA, SD, KS, CO, AZ), it's cash-pay only with no insurance noted, the compounding pharmacy partner isn't named, and no LegitScript certification is shown on the site. As with any GLP-1 program, confirm your state is among the six served before starting the intake; tirzepatide carries labeled warnings for acute pancreatitis, gallbladder disease, and a boxed thyroid C-cell tumor warning — see our guides on Zepbound side effects, the gallbladder risk, and the thyroid cancer warning.
Does the drug work? (Separate from the provider)
Judge the provider on price, oversight and disclosure; judge the molecule on its trials. Tirzepatide's are strong — roughly 15–21% of body weight over 72 weeks in SURMOUNT-11, and better than semaglutide head-to-head2 — but they were run on the brand drug at FDA-approved doses. Our tirzepatide evidence guide has the full picture.
The honest verdict
ZYP Medical's low consult fee and format flexibility are genuine positives, but its six-state footprint sharply limits who can use it, and its pharmacy stays unnamed. For a provider with broader state coverage and a named pharmacy, compare it against Vitara RX or Zera Health. See our best tirzepatide providers ranking for the full field.
Frequently asked questions
How much does tirzepatide cost through ZYP Medical?
$233/month, with a low $50 initial one-hour consultation.
What states does ZYP Medical serve?
Only six: Nebraska, Iowa, South Dakota, Kansas, Colorado, and Arizona.
Does ZYP Medical offer an oral option?
Yes — both injectable and oral tirzepatide.
References(2)
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, and the SURMOUNT-1 Investigators (2022). Tirzepatide Once Weekly for the Treatment of Obesity.. New England Journal of Medicine. PMID: 35658024. https://pubmed.ncbi.nlm.nih.gov/35658024/
- Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Bays HE, et al. (2025). Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5).. New England Journal of Medicine. PMID: 40353578. https://pubmed.ncbi.nlm.nih.gov/40353578/
About the author
Alan Pierce
Clinical Pharmacology Writer
About Tirzepatide Report · How we verify prices · This page last updated August 2026
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.
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